@unpublished {orozco2024IPaspire,
	title = {ASPIRE: Iterative Amortized Posterior Inference for Bayesian Inverse Problems},
	year = {2024},
	month = {5},
	abstract = {Due to their uncertainty quantification, Bayesian solutions to inverse problems are the framework of choice in applications that are risk averse. These benefits come at the cost of computations that are in general, intractable. New advances in machine learning and variational inference (VI) have lowered the computational barrier by learning from examples. Two VI paradigms have emerged that represent different tradeoffs: amortized and non-amortized. Amortized VI can produce fast results but due to generalizing to many observed datasets it produces suboptimal inference results. Non-amortized VI is slower at inference but finds better posterior approximations since it is specialized towards a single observed dataset. Current amortized VI techniques run into a sub-optimality wall that can not be improved without more expressive neural networks or extra training data. We present a solution that enables iterative improvement of amortized posteriors that uses the same networks architectures and training data. The benefits of our method requires extra computations but these remain frugal since they are based on physics-hybrid methods and summary statistics. Importantly, these computations remain mostly offline thus our method maintains cheap and reusable online evaluation while bridging the approximation gap these two paradigms. We denote our proposed method ASPIRE - Amortized posteriors with Summaries that are Physics-based and Iteratively REfined. We first validate our method on a stylized problem with a known posterior then demonstrate its practical use on a high-dimensional and nonlinear transcranial medical imaging problem with ultrasound. Compared with the baseline and previous methods from the literature our method stands out as an computationally efficient and high-fidelity method for posterior inference.},
	keywords = {Amortization Gap, Amortized Variational Inference, Bayesian inference, medical imaging, Normalizing flows, simulation-based inference},
	doi = {10.48550/arXiv.2405.05398},
	author = {Rafael Orozco and Ali Siahkoohi and Mathias Louboutin and Felix J. Herrmann}
}
@unpublished {orozco2024IMAGEbeacon,
	title = {BEACON: Bayesian Experimental design Acceleration with Conditional Normalizing flows - a case study in optimal monitor well placement for CO2 sequestration},
	year = {2024},
	month = {3},
	abstract = {CO2 sequestration is a crucial engineering solution for mitigating climate change. However, the uncertain nature of reservoir properties, necessitates rigorous monitoring of CO2 plumes to prevent risks such as leakage, induced seismicity, or breaching licensed boundaries. To address this, project managers use borehole wells for direct CO2 and pressure monitoring at specific locations. Given the high costs associated with drilling, it is crucial to strategically place a limited number of wells to ensure maximally effective monitoring within budgetary constraints. Our approach for selecting well locations integrates fluid-flow solvers for forecasting plume trajectories with generative neural networks for plume inference uncertainty. Our methodology is extensible to three-dimensional domains and is developed within a Bayesian framework for optimal experimental design, ensuring scalability and mathematical optimality. We use a realistic case study to verify these claims by demonstrating our method{\textquoteright}s application in a large scale domains and optimal performance as compared to baseline well placement.},
	keywords = {Amortized Variational Inference, Bayesian inference, conditional normalizing flows, deep learning, GCS, Inverse problems, OED, Uncertainty quantification},
	doi = {10.48550/arXiv.2404.00075},
	author = {Rafael Orozco and Abhinav Prakash Gahlot and Felix J. Herrmann}
}
@unpublished {zeng2024IMAGEefw,
	title = {Enhancing Full-Waveform Variational Inference through Stochastic Resampling and Data Augmentation},
	year = {2024},
	month = {3},
	keywords = {Amortized Variational Inference, Bayesian inference, CIG, conditional normalizing flows, deep learning, FWI, Imaging, Inverse problems, MVA, RTM, Summary Statistics, Uncertainty quantification, WISE},
	url = {https://slimgroup.github.io/IMAGE2024/Yunlin_Zeng2024SEG/paper.html},
	author = {Yunlin Zeng and Rafael Orozco and Ziyi Yin and Felix J. Herrmann}
}
@article {yin2023wise,
	title = {WISE: full-Waveform variational Inference via Subsurface Extensions},
	journal = {Geophysics},
	year = {2024},
	note = {(GEOPHYSICS)},
	month = {04},
	abstract = {We introduce a probabilistic technique for full-waveform inversion, employing variational inference and conditional normalizing flows to quantify uncertainty in migration-velocity models and its impact on imaging. Our approach integrates generative artificial intelligence with physics-informed common-image gathers, reducing reliance on accurate initial velocity models. Considered case studies demonstrate its efficacy producing realizations of migration-velocity models conditioned by the data. These models are used to quantify amplitude and positioning effects during subsequent imaging.},
	keywords = {Amortized Variational Inference, Bayesian inference, CIG, conditional normalizing flows, deep learning, FWI, Geophysics, Imaging, Inverse problems, MVA, RTM, Summary Statistics, Uncertainty quantification, WISE},
	doi = {10.1190/geo2023-0744.1},
	url = {https://slim.gatech.edu/Publications/Public/Journals/Geophysics/2024/yin2023wise/paper.html},
	author = {Ziyi Yin and Rafael Orozco and Mathias Louboutin and Felix J. Herrmann}
}
@unpublished {yin2024IMAGEwiser,
	title = {WISER: full-Waveform variational Inference via Subsurface Extensions with Refinements},
	year = {2024},
	month = {3},
	abstract = {We introduce a cost-effective Bayesian inference method for full-waveform inversion (FWI) to quantify uncertainty in migration-velocity models and its impact on imaging. Our method targets inverse uncertainty due to null-space of the wave modeling operators and observational noise, and forward uncertainty where the uncertainty in velocity models is propagated to uncertainty in amplitude and positioning of imaged reflectivities. This is achieved by integrating generative artificial intelligence (genAI) with physics-informed common-image gathers (CIGs), which greatly reduces reliance on accurate initial FWI-velocity models. In addition, we illustrate the capability of fine-tuning the generative AI networks with frugal physics-based refinements to improve the inference accuracy.},
	keywords = {Amortized Variational Inference, Bayesian inference, CIG, conditional normalizing flows, deep learning, FWI, Imaging, Inverse problems, MVA, RTM, Summary Statistics, Uncertainty quantification, WISE, WISER},
	url = {https://slimgroup.github.io/IMAGE2024/yin2024SEG/paper.html},
	author = {Ziyi Yin and Rafael Orozco and Mathias Louboutin and Felix J. Herrmann}
}
@unpublished {yin2024wiser,
	title = {WISER: multimodal variational inference for full-waveform inversion without dimensionality reduction},
	year = {2024},
	month = {5},
	abstract = {We present a semi-amortized variational inference framework designed for computationally feasible uncertainty quantification in 2D full-waveform inversion to explore the multimodal posterior distribution without dimensionality reduction. The framework is called WISER, short for full-Waveform variational Inference via Subsurface Extensions with Refinements. WISER leverages the power of generative artificial intelligence to perform approximate amortized inference that is low-cost albeit showing an amortization gap. This gap is closed through non-amortized refinements that make frugal use of acoustic wave physics. Case studies illustrate that WISER is capable of full-resolution, computationally feasible, and reliable uncertainty estimates of velocity models and imaged reflectivities.},
	keywords = {Amortized Variational Inference, Bayesian inference, CIG, conditional normalizing flows, deep learning, FWI, Imaging, Inverse problems, MVA, Summary Statistics, Uncertainty quantification, WISE, WISER},
	doi = {10.13140/RG.2.2.34906.15044},
	url = {https://slim.gatech.edu/Publications/Public/Submitted/2024/yin2024wiser/WISER.html},
	author = {Ziyi Yin and Rafael Orozco and Felix J. Herrmann}
}
@conference {gahlot2023NIPSWSifp,
	title = {Inference of CO2 flow patterns {\textendash} a feasibility study},
	booktitle = {Neural Information Processing Systems (NeurIPS)},
	year = {2023},
	note = {(NeurIPS 2023 Workshop - Tackling Climate Change with Machine Learning (Spotlight))},
	month = {10},
	abstract = {As the global deployment of carbon capture and sequestration (CCS) technology intensifies in the fight against climate change, it becomes increasingly imperative to establish robust monitoring and detection mechanisms for potential underground CO$_2$ leakage, particularly through pre-existing or induced faults in the storage reservoir{\textquoteright}s seals. While techniques such as history matching and time-lapse seismic monitoring of CO$_2$ storage have been used successfully in tracking the evolution of CO$_2$ plumes in the subsurface, these methods lack principled approaches to characterize uncertainties related to the CO$_2$ plumes{\textquoteright} behavior. Inclusion of systematic assessment of uncertainties is essential for risk mitigation for the following reasons: (i) CO$_2$ plume-induced changes are small and seismic data is noisy; (ii) changes between regular and irregular (e.g., caused by leakage) flow patterns are small; and (iii) the reservoir properties that control the flow are strongly heterogeneous and typically only available as distributions. To arrive at a formulation capable of inferring flow patterns for regular and irregular flow from well and seismic data, the performance of conditional normalizing flow will be analyzed on a series of carefully designed numerical experiments. While the inferences presented are preliminary in the context of an early CO$_2$ leakage detection system, the results do indicate that inferences with conditional normalizing flows can produce high-fidelity estimates for CO$_2$ plumes with or without leakage. We are also confident that the inferred uncertainty is reasonable because it correlates well with the observed errors. This uncertainty stems from noise in the seismic data and from the lack of precise knowledge of the reservoir{\textquoteright}s fluid flow properties.},
	keywords = {Amortized Variational Inference, Bayesian inference, CCS, conditional normalizing flows, geological carbon storage, monitoring, NIPS, Summary Statistics},
	doi = {10.48550/arXiv.2311.00290},
	url = {https://slim.gatech.edu/Publications/Public/Conferences/NIPS/2023/gahlot2023NIPSWSifp/paper.pdf},
	presentation = {https://slim.gatech.edu/Publications/Public/Conferences/NIPS/2023/gahlot2023NIPSWSifp/poster.pdf},
	author = {Abhinav Prakash Gahlot and Huseyin Tuna Erdinc and Rafael Orozco and Ziyi Yin and Felix J. Herrmann}
}
@conference {orozco2023AABIiter,
	title = {Refining Amortized Posterior Approximations using Gradient-Based Summary Statistics},
	booktitle = {5th Symposium on Advances in Approximate Bayesian Inference},
	year = {2023},
	note = {(AABI, Honolulu)},
	month = {06},
	abstract = {We present an iterative framework to improve the amortized approximations of posterior distributions in the context of Bayesian inverse problems, which is inspired by loop-unrolled gradient descent methods and is theoretically grounded in maximally informative summary statistics. Amortized variational inference is restricted by the expressive power of the chosen variational distribution and the availability of training data in the form of joint data and parameter samples, which often lead to approximation errors such as the amortization gap. To address this issue, we propose an iterative framework that refines the current amortized posterior approximation at each step. Our approach involves alternating between two steps: (1) constructing a training dataset consisting of pairs of summarized data residuals and parameters, where the summarized data residual is generated using a gradient-based summary statistic, and (2) training a conditional generative model {\textendash} a normalizing flow in our examples {\textendash} on this dataset to obtain a probabilistic update of the unknown parameter. This procedure leads to iterative refinement of the amortized posterior approximations without the need for extra training data. We validate our method in a controlled setting by applying it to a stylized problem, and observe improved posterior approximations with each iteration. Additionally, we showcase the capability of our method in tackling realistically sized problems by applying it to transcranial ultrasound, a high-dimensional, nonlinear inverse problem governed by wave physics, and observe enhanced posterior quality through better image reconstruction with the posterior mean.},
	keywords = {AABI, Amortization Gap, Amortized Variational Inference, Bayesian inference, conditional normalizing flows, Summary Statistics},
	url = {https://arxiv.org/abs/2305.08733},
	presentation = {https://slim.gatech.edu/Publications/Public/Conferences/AABI/2023/orozco2023AABIiter/aabi_poster.pdf},
	author = {Rafael Orozco and Ali Siahkoohi and Mathias Louboutin and Felix J. Herrmann}
}
