@conference {orozco2025SIAMisu,
	title = {Industry-Scale Uncertainty-Aware Full Waveform Inference with Generative Models},
	booktitle = {SIAM Conference on Computational Science and Engineering (CSE25)},
	year = {2025},
	note = {(SIAM CSE25, Dallas)},
	month = {03},
	abstract = {In this talk, we address the challenge of Bayesian sampling for ill-posed inverse problems involving expensive PDE forward operators. To tackle this, we propose the use of generative models and discuss three key challenges along with our solutions. First, we address the constraints of GPU memory by introducing patch-based training and memory-efficient invertible networks, enabling the handling of large-scale data. Second, we demonstrate that these models can be effectively trained using only prior data available from acoustic observations and borehole well data, making the approach practical for real-world applications. Third, we explore various strategies to enhance the reliability of posterior samples by incorporating physics-based constraints through the wave operator. We conclude by presenting experiments that showcase the capabilities of these methods in field-data Full Waveform Inversion (FWI) workflows, scaling up to industry-scale problems with large 2D (512x7000 degrees of freedom) and 3D models.},
	keywords = {Bayesian sampling, FWI, Generative models, Inverse problems, Normalizing flows, SIAM},
	url = {https://slim.gatech.edu/Publications/Public/Conferences/SIAMCSE/2025/orozco2025SIAMisu},
	author = {Rafael Orozco and Huseyin Tuna Erdinc and Mathias Louboutin and Felix J. Herrmann}
}
@unpublished {zeng2025IMAGEw2f,
	title = {Well2Flow: Reconstruction of reservoir states from sparse wells using score-based generative models},
	year = {2025},
	month = {3},
	keywords = {deep learning, diffusion-pde models, Generative models, history matching, reservoir simulation, score, sparse observations, Uncertainty quantification},
	url2 = {https://slim.gatech.edu/Publications/Public/Submitted/2025/zeng2025IMAGEw2f/IMAGE_Shiqin.pdf},
	author = {Shiqin Zeng and Haoyun Li and Abhinav Prakash Gahlot and Felix J. Herrmann}
}
@mastersthesis {orozco2024THgmf,
	title = {GENERATIVE MODELS FOR UNCERTAINTY QUANTIFICATION OF MEDICAL AND SEISMIC IMAGING},
	year = {2024},
	note = {(PhD)},
	month = {12},
	school = {Georgia Institute of Technology},
	type = {phd},
	address = {Atlanta},
	abstract = {This thesis investigates the intersection of machine learning-based generative models with physics-based methods to address imaging problems, with an emphasis on accelerat- ing computations while incorporating uncertainty quantification. Throughout the chapters, a key conclusion emerges: machine learning methods, though powerful, are insufficient when used in isolation. They must be combined with the trusted domain knowledge con- tained in numerical physics simulations to achieve robust results. The methods presented bridge two of the most impactful areas in modern computer science: numerical simula- tions methods rooted in linear algebra and the transformative potential of deep learning, particularly as exemplified by recent advancements in generative modeling. The focus of this work is on scenarios where the underlying physics is computation- ally expensive, requiring frugal use of simulations. This is particularly relevant in high- dimensional, ill-posed inverse problems, such as those encountered in the applications shown in this thesis: medical imaging and seismic exploration, where the forward oper- ator is governed by complex partial differential equations (PDEs). To address these challenges, this thesis introduces techniques that blend practical ma- chine learning approaches with theoretical insights, particularly through the use of physics- based summary statistics. These statistics enable efficient extraction of meaningful in- formation from physics simulations, reducing computational overhead while preserving the critical elements of the physical model. Theoretical foundations underpin the design choices, ensuring that the methods are both efficient and ameliorate the potential bias that would arise from using physics-based summary statistics instead of raw observations. As an engineering-focused work, the thesis places a strong emphasis on practicality and robustness. The proposed methods are stress-tested through validation experiments, on increasingly complex scenarios with a clear pathway toward deployment in the real-world. This applied perspective reflects the ultimate goal of leveraging these methods to create tangible, impactful changes in domains such as healthcare and geophysics. By bridging the gap between advanced machine learning and trusted physics-based methods, this work contributes to the development of innovative tools that balance computational efficiency, uncertainty quantification, and practical applicability.},
	keywords = {Bayesian inference, CCS, CIG, conditional normalizing flows, FWI, GCS, Generative models, Inverse problems, medical imaging, monitoring, Normalizing flows, PhD, RTM, scientific machine learning, time-lapse, Uncertainty quantification, Variational Inference, WISE, WISER},
	url = {https://slim.gatech.edu/Publications/Public/Thesis/2024/orozco2024THgmf/Thesis_Orozco_pdf.pdf},
	presentation = {https://slim.gatech.edu/Publications/Public/Thesis/2024/orozco2024THgmf/defense-real},
	author = {Rafael Orozco}
}
@mastersthesis {yin2024THsgi,
	title = {Solving geophysical inverse problems with scientific machine learning},
	year = {2024},
	note = {(PhD)},
	month = {06},
	school = {Georgia Institute of Technology},
	type = {phd},
	address = {Atlanta},
	abstract = {Solving inverse problems involves estimating unknown parameters of interest from indirect measurements. Specifically, geophysical inverse problems seek to determine various Earth properties critical for geophysical exploration, carbon control, monitoring, and earthquake detection. These problems pose unique challenges: the parameters of interest are often high-dimensional, and the mapping from parameters to observables is computationally demanding. Moreover, these problems are typically non-convex and ill-posed, meaning that multiple sets of model parameters can adequately fit the observations, and inversion algorithms depend on accurate initial model parameters. This thesis introduces several innovative methods to tackle these challenges using scientific machine learning techniques. It discusses algorithms and software frameworks that utilize surrogate and generative models to achieve scalable and reliable inversion. It also examines the integration of conditional generative models with physics for Bayesian variational inference and uncertainty quantification. These methods have been applied to two critical inverse problems in geophysical applications: monitoring geological carbon storage and full-waveform inversion, both of which are plagued by the aforementioned computational challenges. The thesis consists of six papers. The first two papers present a scalable, interoperable, and differentiable programming framework for learned multiphysics inversion, showcased through realistic synthetic case studies in geological carbon storage monitoring. The third paper introduces a computationally efficient and reliable algorithm that employs surrogate models, particularly Fourier neural operators, to accelerate inversion. The reliability of this algorithm is ensured by using normalizing flows as learned constraints to safeguard the accuracy of the surrogate models throughout the inversion process. The subsequent paper explores a joint inversion approach and an explainable deep neural classifier for time-lapse seismic imaging and carbon dioxide leakage detection during geological carbon storage. The final two papers introduce amortized and semi-amortized variational inference approaches that employ information-preserving physics-informed summary statistics and refinements to provide computationally feasible and reliable uncertainty quantification in high-dimensional full-waveform inversion problems. They also assess the impact of the inherent uncertainty in these ill-posed inversion problems on subsequent imaging tasks.},
	keywords = {Bayesian inference, CCS, CIG, conditional normalizing flows, end-to-end, Fourier neural operators, FWI, GCS, Generative models, Inverse problems, JRM, monitoring, Normalizing flows, PhD, RTM, scientific machine learning, time-lapse, Uncertainty quantification, Variational Inference, WISE, WISER},
	url = {https://slim.gatech.edu/Publications/Public/Thesis/2024/yin2024THsgi/yin2024THsgi.pdf},
	presentation = {https://slim.gatech.edu/Publications/Public/Thesis/2024/yin2024THsgi/yin2024THsgi_pres.pdf},
	author = {Ziyi Yin}
}
@mastersthesis {siahkoohi2022THdgmf,
	title = {Deep generative models for solving geophysical inverse problems},
	year = {2022},
	note = {(PhD)},
	month = {07},
	school = {Georgia Institute of Technology},
	type = {phd},
	address = {Atlanta},
	abstract = {My thesis presents several novel methods to facilitate solving large-scale inverse problems by utilizing recent advances in machine learning, and particularly deep generative modeling. Inverse problems involve reliably estimating unknown parameters of a physical model from indirect observed data that are noisy. Solving inverse problems presents primarily two challenges. The first challenge is to capture and incorporate prior knowledge into ill-posed inverse problems whose solutions cannot be uniquely identified. The second challenge is the computational complexity of solving inverse problems, particularly the cost of quantifying uncertainty. The main goal of this thesis is to address these issues by developing practical data-driven methods that are scalable to geophysical applications in which access to high-quality training data is often limited. There are six papers included in this thesis. A majority of these papers focus on addressing computational challenges associated with Bayesian inference and uncertainty quantification, while others focus on developing regularization techniques to improve inverse problem solution quality and accelerate the solution process. These papers demonstrate the applicability of the proposed methods to seismic imaging, a large-scale geophysical inverse problem with a computationally expensive forward operator for which sufficiently capturing the variability in the Earth{\textquoteright}s heterogeneous subsurface through a training dataset is challenging. The first two papers present computationally feasible methods of applying a class of methods commonly referred to as deep priors to seismic imaging and uncertainty quantification. I also present a systematic Bayesian approach to translate uncertainty in seismic imaging to uncertainty in downstream tasks performed on the image. The next two papers aim to address the reliability concerns surrounding data-driven methods for solving Bayesian inverse problems by leveraging variational inference formulations that offer the benefits of fully-learned posteriors while being directly informed by physics and data. The last two papers are concerned with correcting forward modeling errors where the first proposes an adversarially learned postprocessing step to attenuate numerical dispersion artifacts in wave-equation simulations due to coarse finite-difference discretizations, while the second trains a Fourier neural operator surrogate forward model in order to accelerate the qualification of uncertainty due to errors in the forward model parameterization.},
	keywords = {Bayesian inference, deep learning, Generative models, Geophysics, Inverse problems, PhD},
	url = {https://slim.gatech.edu/Publications/Public/Thesis/2022/siahkoohi2022THdgmf/siahkoohi2022THdgmf.pdf},
	presentation = {https://slim.gatech.edu/Publications/Public/Thesis/2022/siahkoohi2022THdgmf/siahkoohi2022THdgmf_pres.pdf},
	author = {Ali Siahkoohi}
}
@conference {siahkoohi2022SEGWSrav,
	title = {Reliable amortized variational inference with conditional normalizing flows via physics-based latent distribution correction},
	booktitle = {IMAGE Workshop on Subsurface Uncertainty Description and Estimation - Moving Away from Single Prediction with Distribution Learning},
	year = {2022},
	note = {(IMAGE Workshop, Houston)},
	month = {09},
	abstract = {Bayesian inference for high-dimensional inverse problems is challenged by the computational costs associated with the forward operator during posterior sampling, as well as the selection of an appropriate prior distribution that encodes our prior knowledge about the unknown. Amortized variational inference addresses these challenges by pretraining a conditional normalizing flow (cNF) that approximates the posterior distribution over the existing model and data joint samples where the prior is implicitly learned from the data. When fed data and normally distributed latent samples as input, the pretrained cNF provides posterior samples for previously unseen data virtually for free. The accuracy of this purely data-driven approach, however, is dependent on the availability of high-fidelity training data, which is rarely the case with geophysical inverse problems, due to the highly heterogeneous structure of the Earth. To overcome this challenge and to minimize the negative bias of data distribution shifts during inference, we propose learning a physics-based correction to the cNF latent distribution to provide a more accurate approximation to the posterior distribution. We accomplish this by parameterizing the cNF latent distribution by a Gaussian distribution with an unknown mean and diagonal covariance, which are estimated by minimizing the Kullback-Leibler divergence between the corrected posterior distribution estimate and the true posterior distribution. For a relatively well-trained cNF, this approach provides reliable posterior samples with a limited computational cost while remaining bound to data and physics. We showcase the computational gains of this approach on a "quasi" real seismic imaging example.},
	keywords = {Bayesian inference, deep learning, Generative models, Imaging, Inverse problems, SEG, Uncertainty quantification, workshop},
	url = {https://www.imageevent.org/Workshop/subsurface-uncertainty-description-estimation-moving-away-single-prediction-distribution-learning},
	presentation = {https://slim.gatech.edu/Publications/Public/Conferences/SEG/2022/siahkoohi2022SEGWSrav/Thur-15-55-Siahkoohi.pdf},
	author = {Ali Siahkoohi and Gabrio Rizzuti and Rafael Orozco and Felix J. Herrmann}
}
