@article {orozco2023invnet,
	title = {InvertibleNetworks.jl: A Julia package for scalable normalizing flows},
	journal = {Journal of Open Source Software},
	volume = {9},
	year = {2024},
	month = {7},
	abstract = {InvertibleNetworks.jl is a Julia package designed for the scalable implementation of normalizing flows, a method for density estimation and sampling in high-dimensional distributions. This package excels in memory efficiency by leveraging the inherent invertibility of normalizing flows, which significantly reduces memory requirements during backpropagation compared to existing normalizing flow packages that rely on automatic differentiation frameworks. InvertibleNetworks.jl has been adapted for diverse applications, including seismic imaging, medical imaging, and CO2 monitoring, demonstrating its effectiveness in learning high-dimensional distributions.},
	keywords = {Bayesian inference, computing, conditional normalizing flows, deep learning, HPC, Inverse problems, memory, Normalizing flows, software, Uncertainty quantification},
	doi = {10.21105/joss.06554},
	url = {https://doi.org/10.21105/joss.06554},
	author = {Rafael Orozco and Philipp A. Witte and Mathias Louboutin and Ali Siahkoohi and Gabrio Rizzuti and Bas Peters and Felix J. Herrmann}
}
@conference {orozco2022SPIEadjoint,
	title = {Adjoint operators enable fast and amortized machine learning based Bayesian uncertainty quantification},
	booktitle = {SPIE Medical Imaging Conference},
	year = {2023},
	note = {(SPIE, San Diego)},
	month = {02},
	abstract = {Machine learning algorithms such as Normalizing Flows, VAEs, and GANs are powerful tools in Bayesian uncertainty quantification (UQ) of inverse problems. Unfortunately, when using these algorithms medical imaging practitioners are faced with the challenging task of manually defining neural networks that can handle complicated inputs such as acoustic data. This task needs to be replicated for different receiver types or configurations since these change the dimensionality of the input. We propose to first transform the data using the adjoint operator {\textemdash}ex: time reversal in photoacoustic imaging (PAI) or back-projection in computer tomography (CT) imaging {\textemdash} then continue posterior inference using the adjoint data as an input now that it has been standardized to the size of the unknown model. This adjoint preprocessing technique has been used in previous works but with minimal discussion on if it is biased. In this work, we prove that conditioning on adjoint data is unbiased for a certain class of inverse problems. We then demonstrate with two medical imaging examples (PAI and CT) that adjoints enable two things: Firstly, adjoints partially undo the physics of the forward operator resulting in faster convergence of an ML based Bayesian UQ technique. Secondly, the algorithm is now robust to changes in the observed data caused by differing transducer subsampling in PAI and number of angles in CT. Our adjoint-based Bayesian inference method results in point estimates that are faster to compute than traditional baselines and show higher SSIM metrics, while also providing validated UQ.},
	keywords = {Amortized Inference, Bayesian inference, deep learning, Inverse problems, machine learning, medical imaging, Normalizing flows, SPIE, Uncertainty quantification},
	url = {https://slim.gatech.edu/Publications/Public/Conferences/SPIE/2023/orozco2022SPIEadjoint/SPIE_2022_adjoint.html},
	author = {Rafael Orozco and Ali Siahkoohi and Gabrio Rizzuti and Tristan van Leeuwen and Felix J. Herrmann}
}
@article {louboutin2023lmi,
	title = {Learned multiphysics inversion with differentiable programming and machine learning},
	journal = {The Leading Edge},
	volume = {42},
	year = {2023},
	note = {(The Leading Edge)},
	month = {07},
	pages = {452-516},
	abstract = {We present the Seismic Laboratory for Imaging and Modeling/Monitoring (SLIM) open-source software framework for computational geophysics and, more generally, inverse problems involving the wave-equation (e.g., seismic and medical ultrasound), regularization with learned priors, and learned neural surrogates for multiphase flow simulations. By integrating multiple layers of abstraction, our software is designed to be both readable and scalable. This allows researchers to easily formulate their problems in an abstract fashion while exploiting the latest developments in high-performance computing. We illustrate and demonstrate our design principles and their benefits by means of building a scalable prototype for permeability inversion from time-lapse crosswell seismic data, which aside from coupling of wave physics and multiphase flow, involves machine learning.},
	keywords = {CCS, deep learning, Fourier neural operators, GCS, Imaging, inversion, invertible networks, machine learning, monitoring, multiphysics, Normalizing flows, SLIM, software, time-lapse},
	url = {https://library.seg.org/doi/10.1190/tle42070474.1},
	presentation = {https://slim.gatech.edu/Publications/Public/Journals/TheLeadingEdge/2023/louboutin2023lmi/le_software.pdf},
	url2 = {https://slim.gatech.edu/Publications/Public/Journals/TheLeadingEdge/2023/louboutin2023lmi/le_software.html},
	author = {Mathias Louboutin and Ziyi Yin and Rafael Orozco and Thomas J. Grady II and Ali Siahkoohi and Gabrio Rizzuti and Philipp A. Witte and Olav M{\o}yner and Gerard J. Gorman and Felix J. Herrmann}
}
@presentation {orozco2022ML4SEISMICaos,
	title = {Adjoint operators as summary functions in amortized Bayesian inference frameworks},
	year = {2022},
	month = {11},
	abstract = {An important concern in seismic inverse problems is the large and varying size of observed data. The large size can cause computational cost concerns and its varying size (such as when changing receiver geometries) implies the need to rerun inference algorithms from scratch for each new observation. Motivated by these two problems, we take inspiration from the statistics literature which commonly relies on summary statistic of observed data. Summary statistic compress the observed data leaving only information needed for inference. In this work, we argue that the adjoint operator provides a natural candidate for a summary function in the context of physics-based inverse problems. We first mathematically show that for certain general assumptions transforming data under the adjoint operator defines a new conditional distribution which preserves the expectations of the original posterior. We validate our hypothesis by evaluating our framework in a learned amortized inference algorithm. Our seismic and medical synthetic experiments show computational gains and increased quality of point estimates using our framework. We discuss statistical metrics that show our learned posterior is well calibrated therefore justifying its use in uncertainty quantification.},
	keywords = {Amortized Inference, Bayesian inference, deep learning, Inverse problems, machine learning, medical imaging, ML4SEISMIC, Normalizing flows, SLIM, Uncertainty quantification},
	url = {https://slim.gatech.edu/Publications/Public/Conferences/ML4SEISMIC/2022/orozco2022ML4SEISMICaos/index.html},
	author = {Rafael Orozco and Mathias Louboutin and Ali Siahkoohi and Gabrio Rizzuti and Felix J. Herrmann}
}
@conference {siahkoohi2022SEGWSrav,
	title = {Reliable amortized variational inference with conditional normalizing flows via physics-based latent distribution correction},
	booktitle = {IMAGE Workshop on Subsurface Uncertainty Description and Estimation - Moving Away from Single Prediction with Distribution Learning},
	year = {2022},
	note = {(IMAGE Workshop, Houston)},
	month = {09},
	abstract = {Bayesian inference for high-dimensional inverse problems is challenged by the computational costs associated with the forward operator during posterior sampling, as well as the selection of an appropriate prior distribution that encodes our prior knowledge about the unknown. Amortized variational inference addresses these challenges by pretraining a conditional normalizing flow (cNF) that approximates the posterior distribution over the existing model and data joint samples where the prior is implicitly learned from the data. When fed data and normally distributed latent samples as input, the pretrained cNF provides posterior samples for previously unseen data virtually for free. The accuracy of this purely data-driven approach, however, is dependent on the availability of high-fidelity training data, which is rarely the case with geophysical inverse problems, due to the highly heterogeneous structure of the Earth. To overcome this challenge and to minimize the negative bias of data distribution shifts during inference, we propose learning a physics-based correction to the cNF latent distribution to provide a more accurate approximation to the posterior distribution. We accomplish this by parameterizing the cNF latent distribution by a Gaussian distribution with an unknown mean and diagonal covariance, which are estimated by minimizing the Kullback-Leibler divergence between the corrected posterior distribution estimate and the true posterior distribution. For a relatively well-trained cNF, this approach provides reliable posterior samples with a limited computational cost while remaining bound to data and physics. We showcase the computational gains of this approach on a "quasi" real seismic imaging example.},
	keywords = {Bayesian inference, deep learning, Generative models, Imaging, Inverse problems, SEG, Uncertainty quantification, workshop},
	url = {https://www.imageevent.org/Workshop/subsurface-uncertainty-description-estimation-moving-away-single-prediction-distribution-learning},
	presentation = {https://slim.gatech.edu/Publications/Public/Conferences/SEG/2022/siahkoohi2022SEGWSrav/Thur-15-55-Siahkoohi.pdf},
	author = {Ali Siahkoohi and Gabrio Rizzuti and Rafael Orozco and Felix J. Herrmann}
}
@conference {witte2021JULIACONmedlj,
	title = {InvertibleNetworks.jl - Memory efficient deep learning in Julia},
	booktitle = {JuliaCon},
	year = {2021},
	note = {(JuliaCon, virtual)},
	month = {07},
	abstract = {We present InvertibleNetworks.jl, an open-source package for invertible neural networks and normalizing flows using memory-efficient backpropagation. InvertibleNetworks.jl uses manually implement gradients to take advantage of the invertibility of building blocks, which allows for scaling to large-scale problem sizes. We present the architecture and features of the library and demonstrate its application to a variety of problems ranging from loop unrolling to uncertainty quantification.},
	keywords = {deep learning, Invertible network, Julia, Normalizing flows, segmentation},
	url = {https://slim.gatech.edu/Publications/Public/Conferences/JuliaCon/2021/witte2021JULIACONmedlj/witte2021JULIACONmedlj.pdf},
	url2 = {https://www.youtube.com/watch?v=9M-zEGHY4i4},
	author = {Philipp A. Witte and Mathias Louboutin and Ali Siahkoohi and Gabrio Rizzuti and Bas Peters and Felix J. Herrmann}
}
@presentation {siahkoohi2021ML4SEISMICmcn,
	title = {Multifidelity conditional normalizing flows for physics-guided Bayesian inference},
	year = {2021},
	month = {11},
	abstract = {We introduce a scalable Bayesian inference approach that combines techniques from deep learning with a physic-based variational inference formulation. Bayesian inference for ill-posed inverse problems is challenged by the high-dimensionality of the unknown, computationally expensive forward operator, and choosing a prior distribution that accurately encodes prior knowledge on the unknown. To handle this situation and to assess uncertainty, we propose to approximate the posterior distribution using a pretrained conditional normalizing flow, which is trained on existing low- and high-fidelity estimations of the unknown. To further improve the accuracy of this approximation, we use transfer learning and finetune this normalizing flow by minimizing the Kullback-Leibler divergence between the predicted and the desired high-fidelity posterior density. This amounts to minimizing a physic-based variational inference objective with respect to the network weights, which we believe might scale better than Bayesian inference with Markov Chain sampling methods. We apply the proposed Bayesian inference approach to seismic imaging where we use quasi-real data obtained from the Parihaka dataset.},
	keywords = {deep learning, ML4SEISMIC, Normalizing flows, seismic imaging, SLIM, Variational Inference},
	url = {https://slim.gatech.edu/Publications/Public/Conferences/ML4SEISMIC/2021/siahkoohi2021ML4SEISMICmcn/Mon-11-45-Siahkoohi.pdf},
	author = {Ali Siahkoohi and Rafael Orozco and Gabrio Rizzuti and Philipp A. Witte and Mathias Louboutin and Felix J. Herrmann}
}
@conference {siahkoohi2020EAGEdlb,
	title = {A deep-learning based Bayesian approach to seismic imaging and uncertainty quantification},
	booktitle = {EAGE Annual Conference Proceedings},
	year = {2020},
	note = {Accepted in EAGE},
	month = {1},
	abstract = {Uncertainty quantification is essential when dealing with ill-conditioned inverse problems due to the inherent nonuniqueness of the solution. Bayesian approaches allow us to determine how likely an estimation of the unknown parameters is via formulating the posterior distribution. Unfortunately, it is often not possible to formulate a prior distribution that precisely encodes our prior knowledge about the unknown. Furthermore, adherence to handcrafted priors may greatly bias the outcome of the Bayesian analysis. To address this issue, we propose to use the functional form of a randomly initialized convolutional neural network as an implicit structured prior, which is shown to promote natural images and excludes images with unnatural noise. In order to incorporate the model uncertainty into the final estimate, we sample the posterior distribution using stochastic gradient Langevin dynamics and perform Bayesian model averaging on the obtained samples. Our synthetic numerical experiment verifies that deep priors combined with Bayesian model averaging are able to partially circumvent imaging artifacts and reduce the risk of overfitting in the presence of extreme noise. Finally, we present pointwise variance of the estimates as a measure of uncertainty, which coincides with regions that are difficult to image.},
	keywords = {deep learning, EAGE, seismic imaging, stochastic gradient Langevin dynamics, Uncertainty quantification},
	url = {https://slim.gatech.edu/Publications/Public/Conferences/EAGE/2020/siahkoohi2020EAGEdlb/siahkoohi2020EAGEdlb.html},
	author = {Ali Siahkoohi and Gabrio Rizzuti and Felix J. Herrmann}
}
@presentation {siahkoohi2020SEGCHAPTERGTdlbuq,
	title = {A deep-learning based Bayesian approach to seismic imaging and uncertainty quantification},
	year = {2020},
	note = {(SEG Student Chapter)},
	abstract = {Uncertainty quantification is essential when dealing with ill-conditioned inverse problems due to the inherent nonuniqueness of the solution. Bayesian approaches allow us to determine how likely an estimation of the unknown parameters is via formulating the posterior distribution. Unfortunately, it is often not possible to formulate a prior distribution that precisely encodes our prior knowledge about the unknown. Furthermore, adherence to handcrafted priors may greatly bias the outcome of the Bayesian analysis. To address this issue, we propose to use the functional form of a randomly initialized convolutional neural network as an implicit structured prior, which is shown to promote natural images and excludes images with unnatural noise. In order to incorporate the model uncertainty into the final estimate, we sample the posterior distribution using stochastic gradient Langevin dynamics and perform Bayesian model averaging on the obtained samples. Our synthetic numerical experiment verifies that deep priors combined with Bayesian model averaging are able to partially circumvent imaging artifacts and reduce the risk of overfitting in the presence of extreme noise. Finally, we present pointwise variance of the estimates as a measure of uncertainty, which coincides with regions that are more difficult to image.},
	keywords = {deep learning, seismic imaging, stochastic gradient Langevin dynamics, Uncertainty quantification},
	url = {https://slim.gatech.edu/Publications/Public/Lectures/SEGCHAPTERGT/2020/siahkoohi2020SEGCHAPTERGTdlbuq/siahkoohi2020SEGCHAPTERGTdlbuq.pdf},
	author = {Ali Siahkoohi and Gabrio Rizzuti and Felix J. Herrmann}
}
@techreport {siahkoohi2020TRfuqf,
	title = {Faster Uncertainty Quantification for Inverse Problems with Conditional Normalizing Flows},
	number = {TR-CSE-2020-2},
	year = {2020},
	month = {07},
	institution = {Georgia Institute of Technology},
	abstract = {In inverse problems, we often have access to data consisting of paired samples $(x,y)\sim p_X,Y(x,y)$ where $y$ are partial observations of a physical system, and $x$ represents the unknowns of the problem. Under these circumstances, we can employ supervised training to learn a solution $x$ and its uncertainty from the observations $y$. We refer to this problem as the "supervised" case. However, the data $y\sim p_Y(y)$ collected at one point could be distributed differently than observations $y{\textquoteright}\sim p_Y{\textquoteright}(y{\textquoteright})$, relevant for a current set of problems. In the context of Bayesian inference, we propose a two-step scheme, which makes use of normalizing flows and joint data to train a conditional generator $q_θ(x|y)$ to approximate the target posterior density $p_X|Y(x|y)$. Additionally, this preliminary phase provides a density function $q_θ(x|y)$, which can be recast as a prior for the "unsupervised" problem, e.g. when only the observations $y{\textquoteright}\sim p_Y{\textquoteright}(y{\textquoteright})$, a likelihood model $y{\textquoteright}|x$, and a prior on $x{\textquoteright}$ are known. We then train another invertible generator with output density $q{\textquoteright}_φ(x|y{\textquoteright})$ specifically for $y{\textquoteright}$, allowing us to sample from the posterior $p_X|Y{\textquoteright}(x|y{\textquoteright})$. We present some synthetic results that demonstrate considerable training speedup when reusing the pretrained network $q_θ(x|y{\textquoteright})$ as a warm start or preconditioning for approximating $p_X|Y{\textquoteright}(x|y{\textquoteright})$, instead of learning from scratch. This training modality can be interpreted as an instance of transfer learning. This result is particularly relevant for large-scale inverse problems that employ expensive numerical simulations.},
	keywords = {deep learning, invertible networks, Uncertainty quantification},
	url = {https://slim.gatech.edu/Publications/Public/TechReport/2020/siahkoohi2020TRfuqf/siahkoohi2020TRfuqf.html},
	author = {Ali Siahkoohi and Gabrio Rizzuti and Philipp A. Witte and Felix J. Herrmann}
}
@conference {siahkoohi2020SIAMTXLAudg,
	title = {Unsupervised data-guided uncertainty analysis in imaging and horizon tracking},
	booktitle = {SIAM Texas-Louisiana},
	year = {2020},
	note = {SIAMTXLA},
	month = {10},
	abstract = {Imaging typically is the first stage of a sequential workflow, and uncertainty quantification becomes more relevant when applied to subsequent tasks. We propose a Bayesian approach to horizon tracking uncertainty analysis, where we deploy a deep prior instead of adhering to handcrafted priors. By passing samples from the posterior distribution obtained via stochastic gradient Langevin dynamics to an automatic horizon tracker, we are able to incorporate the uncertainty on model parameters into horizon tracking.},
	keywords = {deep learning, horizon tracking, McMC, Uncertainty quantification},
	url = {https://slim.gatech.edu/Publications/Public/Conferences/SIAMTXLA/2020/siahkoohi2020SIAMTXLAudg/siahkoohi2020SIAMTXLAudg_pres.pdf},
	author = {Ali Siahkoohi and Gabrio Rizzuti and Mathias Louboutin and Felix J. Herrmann}
}
@conference {herrmann2019NIPSliwcuc,
	title = {Learned imaging with constraints and uncertainty quantification},
	booktitle = {Neural Information Processing Systems (NeurIPS)},
	year = {2019},
	note = {(NIPS, Vancouver)},
	month = {12},
	abstract = {We outline new approaches to incorporate ideas from convolutional networks into wave-based least-squares imaging. The aim is to combine hand-crafted constraints with deep convolutional networks allowing us to directly train a network capable of generating samples from the posterior. The main contributions include combination of weak deep priors with hard handcrafted constraints and a possible new way to sample the posterior.},
	keywords = {constraint, deep learning, Imaging, Uncertainty quantification},
	url = {https://slim.gatech.edu/Publications/Public/Conferences/NIPS/2019/herrmann2019NIPSliwcuc/herrmann2019NIPSliwcuc.html},
	presentation = {https://slim.gatech.edu/Publications/Public/Conferences/NIPS/2019/herrmann2019NIPSliwcuc/herrmann2019NIPSliwcuc_pres.pdf},
	url2 = {https://openreview.net/pdf?id=Hyet2Q29IS},
	author = {Felix J. Herrmann and Ali Siahkoohi and Gabrio Rizzuti}
}
@presentation {herrmann2019HOTCSEliwcuq,
	title = {Learned imaging with constraints and uncertainty quantification},
	year = {2019},
	note = {(HotCSE)},
	abstract = {We outline new approaches to incorporate ideas from convolutional networks into wave-based least-squares imaging. The aim is to combine hand-crafted constraints with deep convolutional networks allowing us to directly train a network capable of generating samples from the posterior. The main contributions include combination of weak deep priors with hard handcrafted constraints and a possible new way to sample the posterior.},
	keywords = {deep learning, Expectation Maximization, HotCSE, Imaging, Uncertainty quantification},
	url = {https://slim.gatech.edu/Publications/Public/Lectures/HotCSE/2019/herrmann2019HOTCSEliwcuq/herrmann2019HOTCSEliwcuq.pdf},
	author = {Felix J. Herrmann and Ali Siahkoohi and Gabrio Rizzuti}
}
